Established Assays
Optimized assay conditions
Flexible
Single/multiple assay in parallel
Cost-effective
Low budget, high quality data
Fast Turnaround Time
Up to 2 weeks
Procedures
Protein Supply
  • Established protein construct in house
  • Tailored high quality assay grade proteins
  • Protein QC: SDS-PAGE, aSEC, MS analysis included
Assay Initiation & Measurements
  • Established assay conditions
  • Established labeling/coupling method
  • Published tool compounds Up to 3 Tms / Kds / IC50s included
Results & Reports
  • A tabulated report included
  • Extended report available including measured curves, assay conditions, analysis and scientific summary in pdf-format
Assay Show Cases
Activity-Validated Assays of NLRP3 vs. MCC95
Impact of MCC95 on NLPR3 thermal stability
LabelFree TSA (nanoDSF)
Control: DMSO MCC95: 1 μM
Binding affinity of MCC95 to NLPR3
Labeled MST assay
KD: 2nM
Impact of MCC95 on NLRP3 activity
ADP Glo assay
IC50: 450 nM
Assay List
Target UniPort ID PP MST nanoDSF SPR Biochemical Assay Price
DOCK5 Q9H7D0 nucleotide exchange
NRAS P01111 nucleotide exchange
PIK3CA P42336 ADP Glo
MALT1 Q9UDY8
CDK7 P50613
STAT3 P40763
STAT6 P42226
STING Q86WV6
USP7 Q93009
SMARCA2 P51531 developing ADP Glo
MAP4K1 Q92918 developing ADP Glo
CRBN/DDB1 Q926SW2/Q16531 developing
SOS1 Q07889 nucleotide exchange
KRAS P01116 nucleotide exchange
NLRP3 Q96P20 ADP Glo
cREL Q96HD1
GLUT1 P11166
GRB2 P62993
P2RX3 P56373
p38 Q15759
PolQ Q75417
SHP2 Q06124
Protein Show Cases
WT SMARCA2 vs. BRM/BRG1 ATP Inhibitor-1
Prime Protein
Production
Biophysical Assay
Biochemical Assay
PolQ – Polymerase domain vs. 5‘ Overhang DNA
Prime Protein
Production
Biophysical Assay
NLRP3 PYD vs. MCC-950
Prime Protein
Production
Biophysical Assay
Biochemical Assay
Protein List
Protein list Uniprot ID HitS ID Tag Expected lead time Expression system Price
3C MB12081 GST 1-3 days E.coli
ABL1_1B DC3222 _TH 1-3 days
ABL1_1B DC3229 HT_ 1-3 days
ABL1_1B DC3965 HT_ 1-3 days
ACADM DC3038 MbpT 1-3 days
AcvR1 DA1795 HT_ 1-3 days
AcvR2a DC1700 HT_ 1-3 days
ALAS2 DC3159 HT_ 1-3 days
ALAS2 DC3159 HT_ 1-3 days
ALAS2 DC3130 HT_ 1-3 days
ALAS2 DC3130 HT_ 1-3 days
Alk-1 DC2631 H_ 1-3 days
Alk-1 DC718 HT_ 1-3 days
ALPK1 MB12097 / 2-3 wks E.coli
APOBEC3B DA3516 HSu_ 1-3 days
APOBEC3B DA3517 _H 1-3 days
APOE DC3412 HTMycFlag_H 1-3 days
APOE DC3414 HTFlag_MycH 1-3 days
APOE DC3415 HTFlag_HaH 1-3 days
APOE DC3416 HTHa_H 1-3 days
APOE DC3424 HMyc_Flag 1-3 days
APOE DC3453 HHa_Flag 1-3 days
APOE DC3576 HHa_Flag 1-3 days
APOE DC3663 HTFlag 1-3 days
APOE DC3664 HTFlag 1-3 days
APOE DC3662 HTFlag 1-3 days
APOE DC3676 HT_ 1-3 days
APOE DC3676 HT_ 1-3 days
APOE DC3962 HT_Avi 1-3 days
APOE DC4028 HTFlag 1-3 days
APOE DC4029 HTFlag 1-3 days
APOE DC4111 HT_ 1-3 days
APOE DC4111 HT_ 1-3 days
APOE DC4112 HT_ 1-3 days
APOE DC4112 HT_ 1-3 days
APOE DC4119 HT_ 1-3 days
APOE DC4119 HT_ 1-3 days
APOE DC4165 HT_ 1-3 days
APOE DC4166 HT_ 1-3 days
APOE DC4763 HT_ 1-3 days
APOE DC4765 HTFlag 1-3 days
APOE DC4818 HT_ 1-3 days
APOE DC4880 HT_Avi 1-3 days
APOE DC3420 HHa_Myc 1-3 days
ASB9 MB12331 His 2-3 wks E.coli
ASGR1 DC3324 _H 1-3 days
ASGR1 DC3435 _H 1-3 days
ASGR1 DC3861 _H 1-3 days
ASK-1 MB12098 His 2-3 wks E.coli
AURKA MB12277 His 1-3 days E.coli
BAK1 DA1925 HT_ 1-3 days
benzonase MB12221 / 2-3 wks E.coli
BirA MB12082 / 1-3 days E.coli
BPTF DA2251 HT_ 1-3 days
b-Raf DC4828 HTvmvGstT_ 1-3 days
b-Raf DC4828 HTvmvGstT_ 1-3 days
b-Raf DC4886 HTvmvGstT_ 1-3 days
b-Raf DC4886 HTvmvGstT_ 1-3 days
b-Raf DC4887 StrepIITvmvGstT_ 1-3 days
b-Raf DC5073 GstTvmvHT_ 1-3 days
BRD4 MB12263 / 1-3 days E.coli
BRD4 DA1946 HT_ 1-3 days
BRD4 DA1946 HT_ 1-3 days
BRD4 MB12262 His 1-3 days E.coli
BRD4 MB12268 His 1-3 days E.coli
BRD4 DA1947 HT_ 1-3 days
BRD4 MB12261 His 1-3 days E.coli
BRD4 MB12264 His 2-3 wks E.coli
BRD9 DA1948 HT_ 1-3 days
C (HBV-D) DA2627 1-3 days
C (HBV-D) DA3291 _TH 1-3 days
CCNT1 DC2668 _H 1-3 days
CDC7 DC4261 1-3 days
CDC7 DC4261 1-3 days
CDC7 DC4265 1-3 days
CDC7 DC4512 _Avi 1-3 days
CDC7 / DBF4 MB12076 / 2-3 wks E.coli
CDC7 / DBF4 MB12092 / 2-3 wks E.coli
CDK1 DC3839 HSu_ 1-3 days
CDK1 DC3839 HSu_ 1-3 days
CDK1 MB12283 / 6-7 wks Insect
CDK12 DC4161 HT_ 1-3 days
CDK2 DE545 HMbpT_ 1-3 days
CDK2 DC3863 HSu_ 1-3 days
CDK2 DC3863 His_SUMO_ 1-3 days
CDK2 DA5350 MbpTAviH_ 1-3 days
CDK2 DA5351 MbpT 1-3 days
CDK2/CCNA2 MB12112+12113 / 6-7 wks Insect
CDK2/CCNA2 MB12112+MB12113 / 6-7 wks Insect
CDK2/CCNE1 MB12112+12114 / 6-7 wks Insect
CDK2/CCNE1 MB12112+MB12114 / 6-7 wks Insect
CDK9 DC3457 HMbpPfuP_ 1-3 days
CK1d DC2595 HT_ 1-3 days
CK1d DA5327 GP64UbEk_AviTEVH 1-3 days
CLK1 DA3141 HT_ 1-3 days
CMA1 DC2825 GP64HUbEk_ 1-3 days
CMA1 DC2891 HGstT_ 1-3 days
CRBN/DDB1 MB12275+MB12276 / 6-7 wks Insect
CRBN/DDB1 MB12275-MB12276 Avi_ 6-7 wks Insect
CRBN/DDB1-biotinylated MB12275+76+91 His_Avi_ 6-7 wks Insect
CRBN/DDB1-cleaved MB12278 / 6-7 wks Insect
CRBN/DDB1-uncleaved MB12174 His 6-7 wks Insect
CREBBP MB12303 / 1-3 days E.coli
CREBBP DA2089 HT_ 1-3 days
CREBBP DA2089 HT_ 1-3 days
CSNK1A1 DE1823 1-3 days
CTNB1 MB12292 His 2-3 wks E.coli
CTSS DC3361 _H 1-3 days
CTSS DC1874 1-3 days
CTSS DC2230 _H 1-3 days
CTSS DC2230 _H 1-3 days
DDB1 MB12229 His 6-7 wks Insect
DJ-1 DE2102 1-3 days
Dyrk1A DE1156 HT_ 1-3 days
EGFR DC2466 H_ 1-3 days
EGFR DC3407 HT_ 1-3 days
EGFR DC3407 HT_ 1-3 days
EGFR DC4275 HT_ 1-3 days
EGFR DC4121 HGstT_ 1-3 days
EGFR DE1336 HT_ 1-3 days
EGFR DC1028 HT_ / HT_ 1-3 days
EGFR DC1028 HT_ / HT_ 1-3 days
EGFR DC2464 H_ 1-3 days
EGFR DC2464 H_ 1-3 days
EGFR MB12077 / 6-7 wks Insect
EGFR MB12109 / 6-7 wks Insect
EGFR-CJR18 MB12110 / 6-7 wks Insect
EGFR-CJR31 MB12111 His 6-7 wks Insect
ER_alpha DC2881 H_ 1-3 days
ER_alpha DE1351 HGstTb_ 1-3 days
FEN1 DC2958 H_ 1-3 days
FER MB12226 His 6-7 wks Insect
FGFR3 DC2985 HT_ 1-3 days
FGFR3 DC2979 H_ 1-3 days
FGFR3 DC2094 _H 1-3 days
FGFR4 DC1980 _H 1-3 days
FMS-1 DC3328 H_ 1-3 days
FMS-1 DI1248 HT_ 1-3 days
FMS-1 DI1250 HT_ 1-3 days
FYN DC3033 H_ 1-3 days
FYN DC3032 HT_ 1-3 days
FYN DC3032 HT_ 1-3 days
FYN DC3034 _H 1-3 days
FYN DC2441 HT_ 1-3 days
FYN DC2440 HT_ 1-3 days
FYN DC2570 H_ 1-3 days
FYN DC2570 H_ 1-3 days
FYN MB12075 / 2-3 wks E.coli
GID4 MB12200 His 2-3 wks E.coli
GRB2 DC4376 HT_ 1-3 days
GRB2 DC4376 HT_ 1-3 days
HDAC-2 DC2640 _H 1-3 days
HECTD3 MB12195 His 2-3 wks E.coli
HMOX1 DE961 1-3 days
HMOX1 DC3538 HT_ 1-3 days
HMOX1 DE396 1-3 days
HSD17B11 DC3997 _H 1-3 days
Hsp90 DC2476 HT_ 1-3 days
HSPA2 DC3720 HT_ 1-3 days
IDH1 DC2597 _H 1-3 days
IDH1 DC2654 _H 1-3 days
IDH1 DC2713 _H 1-3 days
IDH1 DC2722 _H 1-3 days
IDH1 DC2189 _H 1-3 days
IRAK3 MB12296 His 6-7 wks Insect
IRAK4 1-3 days
ITCH MB12181 His 2-3 wks E.coli
Jak-1 DC2011 HTb_ 1-3 days
Jak-1 DE1288 HT_ 1-3 days
Jak-2 DE1804 HT_ 1-3 days
Jak-2 DC3852 _TbH8 1-3 days
JMJD2C DE2169 HT_ 1-3 days
JMJD2C DE1660 HT_ 1-3 days
JMJD2D DE1349 HT_ 1-3 days
Jnk1 DE1535 HT_ 1-3 days
Jnk2 DE1426 HT_ 1-3 days
Jnk2 DE1426 HT_ 1-3 days
Jnk3 DE1477 His_Tv_ 1-3 days
KCTD5 MB12190 His 2-3 wks Ecoli
KEAP1 MB12172 His 1-3 days E.coli
KIT DC3970 HT_ 1-3 days
KIT DC3970 HT_ 1-3 days
KIT DC1371 HT_ 1-3 days
KIT DC1371 HT_ 1-3 days
KIT MB12080 / 6-7 wks Insect
KIT-CLS12 MB12108 / 6-7 wks Insect
KLHL40 MB12173 His 1-3 days E.coli
KRAS_DAJ56 MB12218 His_Avi_ 1-3 days E.coli
KRAS_DAJ57 MB12219 His_Avi_ 2-3 wks E.coli
KRAS-cleaved MB12238 / 1-3 days E.coli
KRAS-cleaved MB12234 / 1-3 days E.coli
KRAS-cleaved MB12236 / 1-3 days E.coli
KRAS-cleaved MB12240 / 1-3 days E.coli
KRAS-cleaved MB12242 / 1-3 days E.coli
KRAS-uncleaved MB12239 His 1-3 days E.coli
KRAS-uncleaved MB12235 His 1-3 days E.coli
KRAS-uncleaved MB12237 His 1-3 days E.coli
KRAS-uncleaved MB12241 His 1-3 days E.coli
KRAS-uncleaved MB12243 His 1-3 days E.coli
LacZ MB12306 His 2-3 wks E.coli
Lck DC962 HT_ 1-3 days
LPP MB12085 His 1-3 days E.coli
MALT1 DC4516 ZzHS3CAviT_ 1-3 days
MALT1 DC2830 _H 1-3 days
MALT1 DC3249 _H 1-3 days
MALT1 DC4520 ZzS3CH_ 1-3 days
MALT1 DC4521 ZzS3C_H 1-3 days
MALT1 DC3649 _H 1-3 days
MALT1 DA5291 ZzHS3C_Avi 1-3 days
MALT1-CXW3 MB12115 / 2-3 wks E.coli
MAP3K7 DC2205 HT_ 1-3 days
MAP3K9 DC2835 HT_ 1-3 days
MAP4K1 DC3250 HSuT_ 1-3 days
MAP4K1 DC3477 HSuT_ 1-3 days
MAP4K1 DE1638 H_ 1-3 days
MAP4K1 MB12282 His 6-7 wks Insect
MapK1 DE457 unknown 1-3 days
MapK1 DE1821 H_ 1-3 days
MapK1 DE1963 1-3 days
MapK1 DE1996 H_ 1-3 days
MAPK13 DC2434 HT_ 1-3 days
MapK6 DE1401 HGstTb_ 1-3 days
MAPKAPK2 DC2200 HGstT_ 1-3 days
Mb21d1 (mouse) DA3878 HTbSu_ 1-3 days
MBP-His6 MB12307 His 1-3 days E.coli
MCL1 DC3057 HTMbp_ 1-3 days
MCL1 DC1960 HT_ 1-3 days
MEK-1 DC2109 HGstP 1-3 days
MEK-1 DC1485 HT_ 1-3 days
MEK-1 DC1485 HT_ 1-3 days
MER DE1112 HTb_ 1-3 days
MER DC3502 HTb_ 1-3 days
Met DC1030 GSTHP_ 1-3 days
MKNK2 DC2061 H_ / HGstT_ 1-3 days
MKNK2 DA1658 GstTb 1-3 days
MLLT1 DE1490 HT_ 1-3 days
MLLT1 DC4350 Su_H 1-3 days
MLLT1 MB12250 His 2-3 wks E.coli
Mpro MB12222 / 2-3 wks E.coli
NEDD4 MB12290 His 2-3 wks E.coli
NEDD4L MB12214 His 2-3 wks E.coli
NLRP1 DC3170 HGstT_ 1-3 days
NRAS MB12105 His 1-3 days E.coli
NRAS MB12107 His 1-3 days E.coli
NRAS/BirA MB12249 His 1-3 days E.coli
NRAS-cleaved MB12246 / 2-3 wks E.coli
NRAS-uncleaved MB12247 His 2-3 wks E.coli
NSD1 DC2162 HT_ 1-3 days
NSD1 DC2619 HT_ 1-3 days
NSD1 DC2703 GstT_ 1-3 days
NSD1 DC2909 HT_ 1-3 days
Nsp7-rep MB12259 / 1-3 days E.coli
Nsp8-rep MB12260 / 1-3 days E.coli
NTRK2 DC2481 HT_ 1-3 days
NTRK2 DC2650 HT_ 1-3 days
Nuclease MB12087 / 2-3 wks E.coli
p38_alpha MB12294 His 2-3 wks E.coli
p38_alpha MB12281 His 2-3 wks E.coli
PADI4 DC2655 HP_ 1-3 days
PADI4 DC2655 HP_ 1-3 days
PADI4 DC2745 HGstP 1-3 days
PADI4 DC2803 HGstP 1-3 days
PAH DC2998 HGstT_ 1-3 days
PAH DC3000 HGstT_ 1-3 days
PAK4 DA2062 GstP 1-3 days
Parp-1 DC4764 HTb_ 1-3 days
Parp-1 DC4764 HTb_ 1-3 days
PDE4B DE1932 HTb_ 1-3 days
PDE9A DC3860 1-3 days
PHF8 DA2090 HThioT_ 1-3 days
PIK3CA DC5225 HT_ 1-3 days
PIK3CA DC5226 HT_ 1-3 days
PIK3CA DC5227 HT_ 1-3 days
PIK3CA DC4134 1-3 days
PIK3CA DC3900 HT_ 1-3 days
PIK3CA DC3900 HT_ 1-3 days
PIK3CA DA3794 HT_ 1-3 days
PIK3CA DC851 HT_ 1-3 days
PIK3CA DC4248 1-3 days
PIK3CA-PIK3R1 MB12285+89 His 6-7 wks Insect
PIK3CD (Mouse) DC1870 HT_ 1-3 days
PIP4K2A DA3795 HT_ 1-3 days
PIP4K2B DC3896 HT_ 1-3 days
PIP4K2B DC3896 HT_ 1-3 days
PIP4K2C DC4363 HT_ 1-3 days
PKA DE989 1-3 days
PKM2 MB12284 His 1-3 days E.coli
Plk-1 DE1574 _H 1-3 days
Plk-1 DE1573 _H 1-3 days
Plk-1 DC4358 HT_ 1-3 days
Plk-1 DC4358 HT_ 1-3 days
Plk-1 MB12078 / 6-7 wks Insect
POLQ MB12269 His 6-7 wks Insect
POLQ MB12270 His 6-7 wks Insect
PPP2R1A MB12100 His 2-3 wks E.coli
PPP2R1A MB12095 His 2-3 wks E.coli
PRKAA1 DC3339 _H 1-3 days
PTPN11 DA3204 1-3 days
PTPN11 DC2417 GstT_H 1-3 days
PTPN11 DC3212 _H 1-3 days
PTPN11 DC3360 _H 1-3 days
PTPN11 DA3203 1-3 days
RET DC2599 HGst3C_ 1-3 days
RET DC2599 HGst3C_ 1-3 days
RET 1-3 days
RET DC2227 HGstT_ 1-3 days
RET MB12079 His_GST_ 6-7 wks Insect
ROR1 DE1296 HT_ 1-3 days
SIK3 MB12273 His 6-7 wks Insect
SIRT2 DC4527 HT_ 1-3 days
SKP2 DC3599 GstTvmv_ 1-3 days
SMYD2 MB12093 His 6-7 wks Insect
SND1 DC3613 HT_ 1-3 days
SND1 DC4679 HTvmvAviT_ 1-3 days
SNF (A. aeolicus) DA2992 _TbH8 1-3 days
SOS1-cleaved MB12244 / 1-3 days E.coli
SOS1-uncleaved MB12245 His 1-3 days E.coli
SPOP MB12198 His 2-3 wks E.coli
Src DC4341 Su_TAvFl3H 1-3 days
Src DC4341 Su_TAvFl3H 1-3 days
Src DC3334 HSu_ 1-3 days
Src DC379 HT_ 1-3 days
Src DC379 HT_ 1-3 days
Src MB12253 / 6-7 wks Insect
STAT6 DC4333 HSu_ 1-3 days
STAT6 DC4340 Su_TAvFl3H 1-3 days
STAT6 DC4340 Su_TAvFl3H 1-3 days
STAT6 DC4457 HTvmvHT_ 1-3 days
STAT6 DC4457 HTvmvHT_ 1-3 days
STAT6 DC4895 HSuH_F 1-3 days
STAT6 DC3169 HGstT_ 1-3 days
STING DA2254 HT_ 1-3 days
STING DA2254 HT_ 1-3 days
STING DC1448 HT_ 1-3 days
STING DC1451 HT_ 1-3 days
STING DC1643 _H 1-3 days
STING DC1643 _H 1-3 days
STING MB12073 / 1-3 days E.coli
STING DC4338 HSu_ 1-3 days
STING DC4338 HSu_ 1-3 days
STING DC1728 _H 1-3 days
SYK _H 1-3 days
TAF1 DA2253 HT_ 1-3 days
TCEB1 / TCEB2 / VHL MB12252 His 1-3 days E.coli
TCEB1/TCEB2/VHL MB12280 His 2-3 wks E.coli
TEV MB12083 His 1-3 days E.coli
TEV MB12169 His 2-3 wks E.coli
TGFBR1 DC1438 HT_ 1-3 days
TGFBR2 DC1644 _H 1-3 days
TNIK DC1976 _H 1-3 days
TVMV MB12086 His 1-3 days E.coli
Tyk-2 DA5335 GstTHTvmv_ 1-3 days
UBE3A MB12175 His 2-3 wks E.coli
ULP1 MB12084 His 1-3 days E.coli
USP21 DA3792 HTb_ 1-3 days
USP7 DA3523 GstP 1-3 days
USP7 DC2191 HGstT_ 1-3 days
USP7 DC2191 HGstT_ 1-3 days
USP7 DC2242 _H 1-3 days
USP7 DA3522 GstP 1-3 days
VHL MB12176 His 1-3 days E.coli
WEE1 DC4200 HT_ 1-3 days
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