BIOPHYSICS
BIOCHEMISTRY
LOGIN
Very diverse technology platform facilitates target validation, enables fast hit finding, hit confirmation, and supports lead series optimization.
The broadest technology suite for hit-finding & confirmation accessible
Binding
MST, SPR, nanoDSF, DSF, ITC, HTRF, TR-FRET, FP, SwitchSense, Mass spectrometry, 1H and 19F NMR
STD (Saturation-Transfer Difference) NMR
STD (Saturation-Transfer Difference) NMR
nanoDSF (differential scanning fluorometry)
nanoDSF (differential scanning fluorometry)
MST (MicroScale Thermophoresis)
MST (MicroScale Thermophoresis)
Kinetics
SPR, HTRF, TR-FRET, SwitchSense
SwitchSense
SwitchSense
SPR (Surface plasmon resonance)
SPR (Surface plasmon resonance)
Thermodynamics
ITC, SPR, MST
Stoichiometry
SPR, ITC, MST
SwitchSense
ITC (Isothermal Titration Calorimetry)
Function
HTRF, TR-FRET, SwitchSense, various biochemical assays
(luminescence, fluorescence, colorimetric read-out)
Bodipy-GTP nucleotide exchange assay
Bodipy-GTP nucleotide exchange assay
ADPglo Assay: Kinase activity
ADPglo Assay: Kinase activity
Protein Quality
nanoDSF, DSF, DLS, Mass spectrometry
Bodipy-GTP nucleotide exchange assay
Bodipy-GTP nucleotide exchange assay
LC-MS
LC-MS
Complete biophysical characterization of your compound series
Comparison of methods
Ready to start your project